Unique technology ensures rapid polymerisation

An efficient sealant needs to polymerise quickly to build up its internal strength to provide a rapidly effective barrier. Unlike other sealants, the polymerisation of Vivostat^® fibrin sealant is activated by a simple pH change, and does not require an enzymic reaction.

Polymerisation rates are therefore much faster than conventional fibrinogen/thrombin systems. Activation of the coagulation cascade initiates crosslinking of the fibrin polymer and Vivostat^® fibrin sealant obtains 80% of its full strength within only 1 minute.

The graph shows the polymerisation rate for Vivostat^® fibrin sealant compared with two conventional sealants.
 

Source: The Vivostat® application system: A comparisson
with conventional fibrin sealant systems.