Protection against proteolytic degradation

The uniqueness of Vivostat PRF^® is largely dependent on the effect and stability of the growth factors contained in the PRF^® solution. Controlling the release of platelet contents over several days requires not only a delivery media but also protection of the platelets against degradation.

The autologous fibrin matrix in Vivostat PRF^® protects endogenous growth factors against proteolytic degradation and thereby preserves their biological activity

 Bioactivity and stability of endogenous fibrogenic factors in platelet-rich fibrin - Lundquist et al. - Wound Repair and Regeneration 2007; 1-8