FAQ - Vivostat® Platelet Rich Fibrin (PRF®)

• When should I draw the 120 ml blood from the patient?

  It is very important that you draw blood from the patient before any surgical procedure is started. It is also very important that the prep-unit with the blood is processed within one hour after drawing.
  
  As soon as the patient is incised the platelets will start to aggregate and this will prevent proper function of the PRF^® preparation.

• Can I draw less than 120 ml blood?

  The system and preparation process are designed based on this specific volume. A reduction in blood volume will reduce the amount of PRF^®. At 60 ml blood no PRF^® will be produced. The Preparation Unit should therefore always be completely filled with 120 ml of blood.

• Can I use plasma if I cannot draw blood?

  No, it is not possible to use plasma as the buffy coat containing the platelets is removed during preparation of the plasma.

• For how long can I use Vivostat PRF®?

  In the majority of cases the PRF^® solution will be used immediately after preparation.
  
  Should the procedure require postponement of the treatment you can store the PRF^® syringe at room temperature for up to 8 hours.
  
  It is very important that you invert the PRF^® syringe 10 times immediately before inserting it in the Applicator Unit to avoid sedimentation of the platelets.

• What is the concentration of platelets and fibrin in Vivostat PRF®?

  The concentration of platelets in Vivostat PRF^® is approximately 7 times the base level of the donor's blood.
  
  In addition, Vivostat PRF^® offers a very high concentration of fibrin - it contains an avarage of 18.1 mg/ml.
  
  This combination of a high concentration of both platelets and fibrin is unobtainable from conventional platelet concentrate systems.

• Are the components in the Vivostat® disposable sets latex free?

  Are the components in the Vivostat^® disposable sets latex free?

  Yes, all disposable components used in the Vivostat^® disposable sets are latex free.

• What is the difference between PRP and PRF?

  PRP (Platelet Rich Plasma) is a conventional platelet concentrate product and, as such, only contains a very low concentration of fibrin. PRF® is a 2. generation platelet product that combines a high concentration of platelets with a high concentration of fibrin – all in one solution. The fibrin matrix present in PRF® provides a number of unique product features, including protection and slow release of the growth factors over time. Furthermore, as the fibrin component in the PRF® solution polymerises immediately upon application, the platelet solution remains precisely where it is applied.