Growth factors and fibrin are essential components when it comes to regeneration of tissue.

Using the Vivostat® System, you can prepare autologous platelets with multiple growth factors embedded in a fibrin sealant matrix. From 120 ml blood, 5-6 ml of Platelet Rich Fibrin (PRF) is prepared. By combining a platelet concentrate with a fibrin sealant solution, it is possible to have a carrier, a controlled release and a medium for vascular ingrowth – all in one product, Vivostat® PRF.

Compared to conventional PRP products, Vivostat® PRF has a number of advantages.

Combining the benefits of platelets and fibrin

With an average 7-fold increase over baseline blood levels, the platelet concentration in Vivostat® PRF exceeds the baseline platelet count of 1 million/μL, which has become a benchmark within platelet therapy. The fibrin matrix ensures a slow release of growth factors over time and effectively protects the growth factors against proteolytic degradation.

Superior application performance

The specially designed Vivostat® Spraypen and the unique combination of platelets and fibrin ensures easy, accurate and efficient application of Vivostat® PRF. Due to instant polymerisation and excellent adhesive properties of the fibrin component, the PRF solution remains where it is applied - even when applied on vertical or inverted surfaces. As the fibrin component in Vivostat® PRF is based on a fibrin 1 solution, there is no need to use a separate thrombin component.

Naturally utilising the combination of platelets and fibrin sealant has many more benefits. These are described under the section Product Characteristics.